Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
نویسندگان
چکیده
منابع مشابه
Protein profile in Aspergillus nidulans recombinant strains overproducing heterologous enzymes
Filamentous fungi are robust cell factories and have been used for the production of large quantities of industrially relevant enzymes. However, the production levels of heterologous proteins still need to be improved. Therefore, this article aimed to investigate the global proteome profiling of Aspergillus nidulans recombinant strains in order to understand the bottlenecks of heterologous enzy...
متن کاملRegulation of the acidic amino acid permease of Aspergillus nidulans.
Chemicals. All chemicals were reagent grade and almost all were obtained from British Drug Houses Ltd, Poole, Dorset. The exceptions were : butyl-PBD [2-(4-tert-butylphenyl)5-(4-biphenylyl)-1, 3,4-oxadiazole] from Koch Light Laboratories Ltd, Colnbrook, Buckinghamshire; malt extract (L 39) and agar no. 3 (L 13) from Oxoid Ltd, London; L-[U-WC]aspartate (227 mCi/mmol), L-[ U-14C]glutamate (I 4.7...
متن کاملAspergillus nidulans
Light-dependent conidiation in the filamentous ascomycete, Aspergillus nidulans, is contingent on the allelic state of the velvet (veA) gene. Light dependence is abolished by a mutation in this gene (veAl) , which allows conidiation to occur in the absence of light. We have isolated and characterized six extragenic suppressors of veAl that restore the light-dependent conidiation phenotype. Alle...
متن کاملPartial Reconstruction of the Ergot Alkaloid Pathway by Heterologous Gene Expression in Aspergillus nidulans
Ergot alkaloids are pharmaceutically and agriculturally important secondary metabolites produced by several species of fungi. Ergot alkaloid pathways vary among different fungal lineages, but the pathway intermediate chanoclavine-I is evolutionarily conserved among ergot alkaloid producers. At least four genes, dmaW, easF, easE, and easC, are necessary for pathway steps prior to chanoclavine-I;...
متن کاملMitosis in Aspergillus nidulans.
Mitosis in growing hyphae of haploid and diploid Aspergillus nidulans has been studied with the light microscope in Helly-fixed preparations. At the periphery of the nucleus a sharply defined granule is invariably found which has strong affinity for acid fuchsin. Mitosis begins with the duplication of this granule and the development inside the nucleus of a gradually lengthening fibre between t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-30816-9